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The absence of Endospanin 1 protein expression protects against harmful alterations associated with obesity
A study conducted by the team “Functional Pharmacology and Pathophysiology of Membrane Receptors” suggests that preferentially favouring lipid uptake in adipocytes can limit the alterations associated with obesity induced by a high-fat diet and promote a "metabolically healthier" obesity. This is dependent on a protein called Endospanin 1, which controls the cellular localisation of the lipid transporter CD36. This work is published in the journal JCI Insight.